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VIOXX® Health Risks - Deep Vein Thrombosis Deep Vein Thrombosis (DVT) and Vioxx® Vioxx® is believed to reduce pain and inflammation by promoting the body's production of prostacyclin. Prostacyclin is a chemical that is believed to reduce pain and inflammation. However, researchers also believe that Cox-2 inhibitors like Vioxx® suppress the formation of an important chemical - prostaglandin I(2) - which is believed to have antithrombotic effects on the blood, i.e. preventing the formation of blood clots. By suppressing the formation of prostaglandin I(2), Vioxx® is believed to promote clotting and the formation of blood clots. This, in turn, increases the risk of thrombotic cardiovascular events - such as heart attack - thrombotic stroke, pulmonary embolism and deep vein thrombosis (DVT). The suppression of anti-clotting agents by Vioxx® is believed to be associated with the development of deep vein thrombosis (DVT) in patients taking Vioxx®. Deep vein thrombosis (DVT) is a condition in which a thrombus, i.e. a blood clot, forms in a deep vein, such as those located in the legs and lower abdomen. When deep vein thrombosis (DVT) develops, the limb or part of the body served by the vein will swell and ache. Swelling and pain are the result of an increase in blood pressure behind the thrombus, i.e. blood clot. The biggest danger associated with deep vein thrombosis (DVT) is that the clot, or a portion of it, may become dislodged, enter the bloodstream and lodge in the lungs, causing pulmonary embolism. Deep vein thrombosis (DVT) can develop in the elderly and others who remain inactive. However, if the body is unable to prevent a blood clot from developing, deep vein thrombosis (DVT) can develop regardless of age or level of activity. Vioxx®, because of its suppression of the body's natural defenses against blood clots, is believed to be associated with the development of deep vein thrombosis (DVT). If you or a loved one has taken Vioxx® and suffered a thrombotic cardiovascular event - such as a heart attack - or a stroke, or developed pulmonary embolism or deep vein thrombosis (DVT), please click here to learn about your legal options. Choose the state where you live to locate a Vioxx lawyer near you. |
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